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FIP200 Antikörper (AA 501-600) (AbBy Fluor® 647)

RB1CC1 Reaktivität: Huhn IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 647
Produktnummer ABIN913131
  • Target Alle FIP200 (RB1CC1) Antikörper anzeigen
    FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))
    Bindungsspezifität
    • 14
    • 11
    • 11
    • 8
    • 7
    • 7
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 501-600
    Reaktivität
    • 29
    • 22
    • 16
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Huhn
    Wirt
    • 54
    • 2
    Kaninchen
    Klonalität
    • 54
    • 2
    Polyklonal
    Konjugat
    • 21
    • 6
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FIP200 Antikörper ist konjugiert mit AbBy Fluor® 647
    Applikation
    • 35
    • 29
    • 12
    • 12
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Huhn
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human RB1CC1
    Isotyp
    IgG
    Top Product
    Discover our top product RB1CC1 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))
    Andere Bezeichnung
    RB1CC1 (RB1CC1 Produkte)
    Synonyme
    DKFZp459E2330 antikoerper, CC1 antikoerper, FIP200 antikoerper, 2900055E04Rik antikoerper, 5930404L04Rik antikoerper, Cc1 antikoerper, LaXp180 antikoerper, RB1 inducible coiled-coil 1 antikoerper, RB1 inducible coiled-coil 1 L homeolog antikoerper, RB1-inducible coiled-coil 1 antikoerper, RB1CC1 antikoerper, rb1cc1.L antikoerper, rb1cc1 antikoerper, Rb1cc1 antikoerper
    Hintergrund

    Synonyms: CC1, ATG17, FIP200, PPP1R131, RB1-inducible coiled-coil protein 1, FAK family kinase-interacting protein of 200 kDa, RB1CC1, KIAA0203, RBICC

    Background: Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111. Involved in autophagy. Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1. Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) duting S.typhimurium infection and subsequent xenophagy. Autophagy positively regulates repair of DNA damage induced by ionizing radiation and negatively regulates apoptosis. Plays an indispensible role in fetal hematopoiesis and in the regulation of neuronal homeostasis (By similarity). Implicated in the regulation of RB1 expression. Functions as a DNA-binding transcription factor. Is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. Expression is, thus, a prerequisite for myogenic differentiation. Inhibits PTK2/FAK1 and PTK2B/PYK2 activity and activation of downstream signaling pathways.

    Gen-ID
    9821
    UniProt
    Q8TDY2
    Pathways
    Regulation of Cell Size, Autophagie
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