RBM38 Antikörper (AA 51-150) (Biotin)

Produktnummer ABIN913185

Produktdetails anti-RBM38 Antikörper (Biotin)

Target: RBM38 (RNA Binding Motif Protein 38 (RBM38))

Bindungsspezifität: AA 51-150

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBM38 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RBM38

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu RBM38

Target: RBM38 (RNA Binding Motif Protein 38 (RBM38))

Andere Bezeichnung: RBM38 (RBM38 Produkte)

Synonyme: rnpc1 antikoerper, seb4b antikoerper, seb4d antikoerper, XSeb4R antikoerper, MGC89204 antikoerper, hsrnaseb antikoerper, YF-55 antikoerper, fi25e12 antikoerper, wu:fi25e12 antikoerper, zgc:92336 antikoerper, xseb4r antikoerper, HSRNASEB antikoerper, RNPC1 antikoerper, SEB4B antikoerper, SEB4D antikoerper, dJ800J21.2 antikoerper, Rnpc1 antikoerper, Seb4 antikoerper, Seb4l antikoerper, RNA binding motif protein 38 antikoerper, RNA binding motif protein 38 L homeolog antikoerper, rbm38 antikoerper, rbm38.L antikoerper, RBM38 antikoerper, Rbm38 antikoerper

Hintergrund:

Synonyms: SEB4D, CLL associated antigen KW 5, CLL-associated antigen KW-5, HSRNASEB, RBM38, RBM38_HUMAN, RNA binding mot protein 38, RNA binding protein 38, RNA binding region RNP1, RRM containing 1, RNA binding region containing protein 1, RNA-binding mot protein 38, RNA-binding protein 38, RNA-binding region-containing protein 1, RNPC1, SEB4, SEB4B, ssDNA binding protein SEB4, ssDNA-binding protein SEB4.

Background: RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation.

Gen-ID: 55544

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development