C14orf166 Antikörper (AA 151-244) (AbBy Fluor® 647)
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- Target Alle C14orf166 Antikörper anzeigen
- C14orf166 (Chromosome 14 Open Reading Frame 166 (C14orf166))
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Bindungsspezifität
- AA 151-244
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser C14orf166 Antikörper ist konjugiert mit AbBy Fluor® 647
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Applikation
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human
- Homologie
- Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human RLLM1/C14orf166
- Isotyp
- IgG
- Top Product
- Discover our top product C14orf166 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- C14orf166 (Chromosome 14 Open Reading Frame 166 (C14orf166))
- Andere Bezeichnung
- RLLM1 (C14orf166 Produkte)
- Synonyme
- CGI99 antikoerper, CLE antikoerper, CLE7 antikoerper, LCRP369 antikoerper, RLLM1 antikoerper, C14orf166 antikoerper, C10H14orf166 antikoerper, RNA transcription, translation and transport factor antikoerper, chromosome 5 C14orf166 homolog antikoerper, RNA transcription, translation and transport factor S homeolog antikoerper, zgc:56576 antikoerper, RTRAF antikoerper, C5H14orf166 antikoerper, rtraf.S antikoerper, zgc:56576 antikoerper
- Hintergrund
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Synonyms: CGI 99, CGI99, CLE, Homeobox prox 1, RLLM1, Chromosome 14 open reading frame 166, CLE7, LCRP369, RLL mot containing 1, CN166_HUMAN.
Background: CGI-99 is a 244 amino acid protein that localizes to the nucleus, as well as to the cytoplasm, and belongs to the UPF0568 family. Expressed in a variety of tissues with particularly high levels in heart and skeletal muscle, CGI-99 functions as a homodimer that interacts with Ninein and is thought to regulate Ninein function. CGI-99 is overexpressed in brain tumor tissue, suggesting a role in tumor development and metastasis. The gene encoding CGI-99 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5 % of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
- Gen-ID
- 51637
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