RORB Antikörper (AA 385-470) (AbBy Fluor® 488)
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- Target Alle RORB Antikörper anzeigen
- RORB (RAR-Related Orphan Receptor B (RORB))
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Bindungsspezifität
- AA 385-470
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Reaktivität
- Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RORB Antikörper ist konjugiert mit AbBy Fluor® 488
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Maus, Ratte
- Homologie
- Human,Dog,Cow,Sheep,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human RORB
- Isotyp
- IgG
- Top Product
- Discover our top product RORB Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- RORB (RAR-Related Orphan Receptor B (RORB))
- Andere Bezeichnung
- ROR beta (RORB Produkte)
- Synonyme
- RORB antikoerper, Nr1f2 antikoerper, LOC100226267 antikoerper, NR1F2 antikoerper, ROR-BETA antikoerper, RZR-BETA antikoerper, RZRB antikoerper, bA133M9.1 antikoerper, nr1f2 antikoerper, rzrb antikoerper, sb:eu943 antikoerper, RZR-beta antikoerper, Rorbeta antikoerper, RAR related orphan receptor B antikoerper, RAR-related orphan receptor B antikoerper, RAR-related orphan receptor beta antikoerper, RORB antikoerper, Rorb antikoerper, rorb antikoerper
- Hintergrund
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Synonyms: NR1F2, Nuclear receptor ROR-beta, Nuclear receptor RZR beta, Nuclear receptor RZR-beta, Nuclear receptor subfamily 1 group F member 2, RAR related orphan receptor B, RAR related orphan receptor beta, Retinoic acid binding receptor beta, Retinoid-related orphan receptor-beta, ROR BETA, Rorb, RORB_HUMAN, RZR BETA, RZRB.
Background: Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Considered to have intrinsic transcriptional activity, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity. Required for normal postnatal development of rod and cone photoreceptor cells. Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated pathway. In cone photoreceptor cells, regulates transcription of OPN1SW. Involved in the regulation of the period length and stability of the circadian rhythm. May control cytoarchitectural patterning of neocortical neurons during development. May act in a dose-dependent manner to regulate barrel formation upon innervation of layer IV neurons by thalamocortical axons. May play a role in the suppression of osteoblastic differentiation through the inhibition of RUNX2 transcriptional activity (By similarity)
- Gen-ID
- 6096
- UniProt
- Q92753
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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