DCUN1D1 Antikörper (AA 101-200) (AbBy Fluor® 350)
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- Target Alle DCUN1D1 Antikörper anzeigen
- DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))
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Bindungsspezifität
- AA 101-200
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DCUN1D1 Antikörper ist konjugiert mit AbBy Fluor® 350
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Horse,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human SCRO/DCUN1D1
- Isotyp
- IgG
- Top Product
- Discover our top product DCUN1D1 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))
- Andere Bezeichnung
- SCRO (DCUN1D1 Produkte)
- Synonyme
- fd19a01 antikoerper, zgc:66414 antikoerper, wu:fd19a01 antikoerper, dcun1l1 antikoerper, rp42 antikoerper, sccro antikoerper, scro antikoerper, tes3 antikoerper, DCNL1 antikoerper, DCUN1L1 antikoerper, RP42 antikoerper, SCCRO antikoerper, SCRO antikoerper, Tes3 antikoerper, Rp42 antikoerper, pTes3 antikoerper, DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) antikoerper, DCN1-like protein 1 antikoerper, DCN1, defective in cullin neddylation 1, domain containing 1 L homeolog antikoerper, defective in cullin neddylation 1 domain containing 1 antikoerper, dcun1d1 antikoerper, dcnl1 antikoerper, dcun1d1.L antikoerper, DCUN1D1 antikoerper, Dcun1d1 antikoerper
- Hintergrund
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Synonyms: DCN1 defective in cullin neddylation 1 domain containing 1, DCN1 like protein 1, DCUN1 domain containing protein 1, DCUN1L1, Defective in cullin neddylation protein 1 like protein 1, RP 42, RP42, RP42 homolog, SCCRO, SCRO, Squamous cell carcinoma related oncogene, Tes 3, Tes3.
Background: DCUN1D1 (DCUN1 domain-containing protein 1) contains a DUF298 domain and a UBA-like ubiquitin. Forms part of an E3 ubiquitin ligase complex for neddylation. Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation. Functions to recruit the NEDD8-charged E2 enzyme to the cullin component. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression. Defects in DCUN1D1 may be a cause of squamous cell carcinomas.Strongly overexpressed in thyroid tumors, bronchioloalveolar carcinomas, and malignant tissues of squamous cell carcinoma of the oral tongue. Not overexpressed in aggressive adrenocortical carcinomas.
- Gen-ID
- 54165
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