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TNIP2 Antikörper (AA 85-180) (AbBy Fluor® 647)

TNIP2 Reaktivität: Human, Ratte WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 647
Produktnummer ABIN918179
  • Target Alle TNIP2 Antikörper anzeigen
    TNIP2 (TNFAIP3 Interacting Protein 2 (TNIP2))
    Bindungsspezifität
    • 14
    • 8
    • 7
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 85-180
    Reaktivität
    • 46
    • 23
    • 13
    • 1
    Human, Ratte
    Wirt
    • 48
    Kaninchen
    Klonalität
    • 48
    Polyklonal
    Konjugat
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TNIP2 Antikörper ist konjugiert mit AbBy Fluor® 647
    Applikation
    • 37
    • 20
    • 12
    • 12
    • 8
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Ratte
    Homologie
    Mouse,Dog,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human TNIP2/ABIN2
    Isotyp
    IgG
    Top Product
    Discover our top product TNIP2 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    TNIP2 (TNFAIP3 Interacting Protein 2 (TNIP2))
    Andere Bezeichnung
    TNIP2 (TNIP2 Produkte)
    Synonyme
    MGC83548 antikoerper, TNIP2 antikoerper, ABIN2 antikoerper, FLIP1 antikoerper, KLIP antikoerper, 1810020H16Rik antikoerper, ABIN-2 antikoerper, AI428870 antikoerper, TNFAIP3 interacting protein 2 antikoerper, TNFAIP3 interacting protein 2 L homeolog antikoerper, TNIP2 antikoerper, tnip2.L antikoerper, tnip2 antikoerper, Tnip2 antikoerper
    Hintergrund

    Synonyms: KLIP, ABIN2, FLIP1, TNFAIP3-interacting protein 2, A20-binding inhibitor of NF-kappa-B activation 2, ABIN-2, Fetal liver LKB1-interacting protein, TNIP2

    Background: Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector NEMO/IKBKG. Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation. Involved in activation of the MEK/ERK signaling pathway during innate immune response, this function seems to be stimulus- and cell type specific. Required for stability of MAP3K8. Involved in regulation of apoptosis in endothelial cells, promotes TEK agonist-stimulated endothelial survival. May act as transcriptional coactivator when translocated to the nucleus. Enhances CHUK-mediated NF-kappa-B activation involving NF-kappa-B p50-p65 and p50-c-Rel complexes.

    Gen-ID
    79155
    UniProt
    Q8NFZ5
    Pathways
    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin
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