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TRIB3 Antikörper (AA 201-300) (Biotin)

TRIB3 Reaktivität: Human, Ratte ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN918607
  • Target Alle TRIB3 Antikörper anzeigen
    TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
    Bindungsspezifität
    • 15
    • 12
    • 10
    • 8
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 201-300
    Reaktivität
    • 68
    • 27
    • 21
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Ratte
    Wirt
    • 75
    • 5
    Kaninchen
    Klonalität
    • 77
    • 3
    Polyklonal
    Konjugat
    • 36
    • 7
    • 6
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TRIB3 Antikörper ist konjugiert mit Biotin
    Applikation
    • 53
    • 40
    • 14
    • 13
    • 13
    • 13
    • 10
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human, Ratte
    Homologie
    Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human TRIB3
    Isotyp
    IgG
    Top Product
    Discover our top product TRIB3 Primärantikörper
  • Applikationshinweise
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
    Andere Bezeichnung
    TRIB3 (TRIB3 Produkte)
    Synonyme
    zgc:76966 antikoerper, TRIB3 antikoerper, C20orf97 antikoerper, NIPK antikoerper, SINK antikoerper, SKIP3 antikoerper, TRB3 antikoerper, Ifld2 antikoerper, Nipk antikoerper, TRB-3 antikoerper, Trb3 antikoerper, tribbles pseudokinase 3 antikoerper, trib3 antikoerper, TRIB3 antikoerper, Trib3 antikoerper
    Hintergrund

    Synonyms: C20orf97, Neuronal cell death inducible putative kinase, Neuronal cell death-inducible putative kinase, NIPK, p65 interacting inhibitor of NF-kappaB, p65-interacting inhibitor of NF-kappa-B, SINK, SKIP 3, SKIP3, TRB 3, TRB-3, TRB3, TRIB 3, Trib3, TRIB3_HUMAN, Tribbles homolog 3, Tribbles3.

    Background: Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regulates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity.Tissue specificity:Highest expression in liver, pancreas, peripheral blood leukocytes and bone marrow. Also highly expressed in a number of primary lung, colon and breast tumors. Expressed in spleen, thymus, and prostate and is undetectable in other examined tissues, including testis, ovary, small intestine, colon, leukocyte, heart, brain, placenta, lung, skeletal muscle, and kidney.

    Gen-ID
    57761
    Pathways
    Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Lipid Metabolism by PPARalpha
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