VLDLR Antikörper (PE-Cy5.5)

Produktnummer ABIN919767

Produktdetails anti-VLDLR Antikörper (PE-Cy5.5)

Target: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Reaktivität: Human, Ratte, Maus, Hund, Schwein, Huhn, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VLDLR Antikörper ist konjugiert mit PE-Cy5.5

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human VLDL Receptor

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:100-500)
FCM(1:100-500)
IHC-P(1:100-500)
IF(IHC-P)(1:100-500)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-VLDLR Antikörper (PE-Cy5.5) (ABIN919767)

Fredriksson, Mishra, Lam, Mushaben, Cuento, Meyer, Yao, Keeran, Nugent, Qu, Yu, Yang, Raghavachari, Dagur, McCoy, Levine: "The very low density lipoprotein receptor attenuates house dust mite-induced airway inflammation by suppressing dendritic cell-mediated adaptive immune responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 10, pp. 4497-509, (2014) (PubMed).

Details zu VLDLR

Target: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Andere Bezeichnung: VLDL Receptor (VLDLR Produkte)

Synonyme: CARMQ1 antikoerper, CHRMQ1 antikoerper, VLDLRCH antikoerper, AA408956 antikoerper, AI451093 antikoerper, AW047288 antikoerper, vldlr antikoerper, very low density lipoprotein receptor antikoerper, very low density lipoprotein receptor S homeolog antikoerper, VLDLR antikoerper, Vldlr antikoerper, vldlr.S antikoerper

Hintergrund:

Synonyms: CARMQ1, CHRMQ1, VLDLRCH, Very low-density lipoprotein receptor, VLDL receptor, VLDL-R, VLDLR

Background: Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity).

Molekulargewicht: 95-130kDa

Gen-ID: 7436

UniProt: P98155

Pathways: Cellular Response to Molecule of Bacterial Origin