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MLXIPL Antikörper (AA 81-180) (AbBy Fluor® 350)

MLXIPL Reaktivität: Ratte IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 350
Produktnummer ABIN919907
  • Target Alle MLXIPL Antikörper anzeigen
    MLXIPL (MLX Interacting Protein-Like (MLXIPL))
    Bindungsspezifität
    • 14
    • 14
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 81-180
    Reaktivität
    • 42
    • 23
    • 12
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Ratte
    Wirt
    • 53
    • 3
    Kaninchen
    Klonalität
    • 53
    • 3
    Polyklonal
    Konjugat
    • 24
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MLXIPL Antikörper ist konjugiert mit AbBy Fluor® 350
    Applikation
    • 32
    • 20
    • 19
    • 12
    • 12
    • 10
    • 8
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Ratte
    Homologie
    Human,Mouse,Dog,Cow,Pig,Horse,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human WBSCR14/ChREBP
    Isotyp
    IgG
    Top Product
    Discover our top product MLXIPL Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    MLXIPL (MLX Interacting Protein-Like (MLXIPL))
    Andere Bezeichnung
    WBSCR14 (MLXIPL Produkte)
    Synonyme
    ChREBP antikoerper, MLXIPL antikoerper, CHREBP antikoerper, MIO antikoerper, MONDOB antikoerper, WBSCR14 antikoerper, WS-bHLH antikoerper, bHLHd14 antikoerper, Wbscr14 antikoerper, MLX interacting protein-like antikoerper, MLX interacting protein like antikoerper, MLXIPL antikoerper, Mlxipl antikoerper
    Hintergrund

    Synonyms: ChREBP, bHLHd14, Carbohydrate responsive element binding protein, MIO, MLX interacting protein like, Mlx interactor, MLXIPL, MONDOB, WBSCR 14, WBSCR14, Williams Beuren syndrome chromosome region 14, Williams Beuren syndrome chromosome region 14 protein, WS basic helix loop helix leucine zipper protein, WS bHLH, MLXPL_HUMAN.

    Background: ChREBP (Carbohydrate responsive element binding protein) is a transcription factor playing a critical role in the nutrient and hormonal regulation of genes encoding enzymes of glucose metabolism and lipogenesis pathways. It contains several domains including a nuclear localization signal (NLS) near the N-terminus, polyproline domains, a basic helix-loop-helix leucine zipper (b/HLH/Zip) and a leucine zipper like (zip-like) domain.ChREBP is ubiquitously detected in various tissues, with highest expression in liver, kidney and white and brown adipose tissue. Under basal conditions ChREBP is localized in the cytosol, translocating into the nucleus upon high glucose stimulation following its dephosphorylation of serine 196.

    Gen-ID
    51085
    Pathways
    Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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