SUPT16H Antikörper (N-Term)

Produktnummer ABIN925767

Produktdetails anti-SUPT16H Antikörper

Target: SUPT16H (FACT complex subunit SPT16 (SUPT16H))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Zebrafisch (Danio rerio), Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SUPT16H Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Hund, Maus, Ratte (Rattus), Zebrafisch (Brachydanio rerio), Frosch, Rind (Kuh)

Immunogen: SUPT16 H antibody was raised in rabbit using the N terminal of SUPT16 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 1.25 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

SUPT16H Blocking Peptide, catalog no. 33R-1511, is also available for use as a blocking control in assays to test for specificity of this SUPT16H antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu SUPT16H

Target: SUPT16H (FACT complex subunit SPT16 (SUPT16H))

Andere Bezeichnung: SUPT16H (SUPT16H Produkte)

Hintergrund: Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit, the latter of which is SUPT16H. Synonyms: Polyclonal SUPT16H antibody, Anti-SUPT16H antibody, suppressor of Ty 16 homolog, S. cerevisiae antibody, CDC68 antibody, FACT antibody, FACTP140 antibody, FLJ10857 antibody, FLJ14010 antibody, FLJ34357 antibody, SPT16/CDC68 antibody.

Pathways: Chromatin Binding