TIMELESS Antikörper (C-Term)

Produktnummer ABIN925900

Produktdetails anti-TIMELESS Antikörper

Target: TIMELESS (Timeless Homolog (TIMELESS))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Drosophila melanogaster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIMELESS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Ratte (Rattus), Maus, Fruchtfliege (Drosophila melanogaster), Hund

Immunogen: TIMELESS antibody was raised in rabbit using the C terminal of TIMELESS as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 2.5 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

TIMELESS Blocking Peptide, catalog no. 33R-2343, is also available for use as a blocking control in assays to test for specificity of this TIMELESS antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu TIMELESS

Target: TIMELESS (Timeless Homolog (TIMELESS))

Andere Bezeichnung: TIMELESS (TIMELESS Produkte)

Hintergrund: The human Timeless protein interacts with both the circadian clock protein cryptochrome 2 and with the cell cycle checkpoint proteins Chk1 and the ATR-ATRIP complex and plays an important role in the DNA damage checkpoint response. Down-regulation of Timeless in human cells seriously compromises replication and intra-S checkpoints, indicating an intimate connection between the circadian cycle and the DNA damage checkpoints that is in part mediated by the Timeless protein. Synonyms: Polyclonal TIMELESS antibody, Anti-TIMELESS antibody, timeless homolog, Drosophila antibody.

Pathways: Protein targeting to Nucleus, Photoperiodism