Topoisomerase II alpha Antikörper (C-Term)
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- Target Alle Topoisomerase II alpha (TOP2A) Antikörper anzeigen
- Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte, Schwein, Hund
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Topoisomerase II alpha Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Hund, Ratte (Rattus), Maus, Schwein
- Immunogen
- TOP2 A antibody was raised in rabbit using the C terminal of TOP2 as the immunogen
- Top Product
- Discover our top product TOP2A Primärantikörper
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- Applikationshinweise
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WB: 1.25 µg/mL
Optimal conditions should be determined by the investigator. - Kommentare
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TOP2A Blocking Peptide, catalog no. 33R-9809, is also available for use as a blocking control in assays to test for specificity of this TOP2A antibody
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Konzentration
- Lot specific
- Buffer
- Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))
- Andere Bezeichnung
- TOP2A (TOP2A Produkte)
- Synonyme
- TOP2 antikoerper, TP2A antikoerper, TOP2A antikoerper, Top-2 antikoerper, TOP-2 antikoerper, F12B17.110 antikoerper, F12B17_110 antikoerper, thimet metalloendopeptidase 2 antikoerper, fc08c07 antikoerper, wu:fc08c07 antikoerper, DNA topoisomerase II alpha antikoerper, DNA topoisomerase II, alpha isozyme antikoerper, topoisomerase (DNA) II alpha antikoerper, Zincin-like metalloproteases family protein antikoerper, TOP2A antikoerper, Bm1_08705 antikoerper, Top2a antikoerper, AT5G10540 antikoerper, top2a antikoerper
- Hintergrund
- TOP2A is a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromsome 17 and the beta gene is localized to chromosome 3. Synonyms: Polyclonal TOP2A antibody, Anti-TOP2A antibody, topoisomerase, DNA II alpha 170kDa antibody.
- Pathways
- Zellzyklus, Mitotic G1-G1/S Phases
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