DDB2 Antikörper (C-Term)

Produktnummer ABIN926426

Produktdetails anti-DDB2 Antikörper

Target: DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Purified

Immunogen: DDB2 antibody was raised in rabbit using the C terminal of DDB2 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

DDB2 Blocking Peptide, catalog no. 33R-4210, is also available for use as a blocking control in assays to test for specificity of this DDB2 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu DDB2

Target: DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))

Andere Bezeichnung: DDB2 (DDB2 Produkte)

Synonyme: 2610043A19Rik antikoerper, si:dkey-45f10.3 antikoerper, DDBB antikoerper, UV-DDB2 antikoerper, damage specific DNA binding protein 2 antikoerper, damage-specific DNA binding protein 2 antikoerper, DDB2 antikoerper, ddb2 antikoerper, Ddb2 antikoerper

Hintergrund: This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Synonyms: Polyclonal DDB2 antibody, Anti-DDB2 antibody, damage-specific DNA binding protein 2, 48kDa antibody, DDBB antibody, FLJ34321 antibody, UV-DDB2 antibody.

Pathways: DNA Reparatur