TCHP Antikörper (C-Term)

Produktnummer ABIN926521

Produktdetails anti-TCHP Antikörper

Target: TCHP (Trichoplein, Keratin Filament Binding (TCHP))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCHP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Purified

Immunogen: TCHP antibody was raised in rabbit using the C terminal of TCHP as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

TCHP Blocking Peptide, catalog no. 33R-4111, is also available for use as a blocking control in assays to test for specificity of this TCHP antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu TCHP

Target: TCHP (Trichoplein, Keratin Filament Binding (TCHP))

Andere Bezeichnung: TCHP (TCHP Produkte)

Synonyme: TpMs antikoerper, A930031F18Rik antikoerper, AV279199 antikoerper, RGD1310813 antikoerper, zgc:136634 antikoerper, trichoplein keratin filament binding antikoerper, trichoplein, keratin filament binding antikoerper, trichoplein, keratin filament binding L homeolog antikoerper, TCHP antikoerper, tchp antikoerper, Tchp antikoerper, tchp.L antikoerper

Hintergrund: TCHP is a tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. It inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. It may act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. And it also may regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells. Synonyms: Polyclonal TCHP antibody, Anti-TCHP antibody, trichoplein, keratin filament binding antibody, MGC10854 antibody.