RCC1 Antikörper (C-Term)

Produktnummer ABIN926713

Produktdetails anti-RCC1 Antikörper

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RCC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Purified

Immunogen: RCC1 antibody was raised in rabbit using the C terminal of RCC1 as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

RCC1 Blocking Peptide, catalog no. 33R-1623, is also available for use as a blocking control in assays to test for specificity of this RCC1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu RCC1

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Andere Bezeichnung: RCC1 (RCC1 Produkte)

Hintergrund: RCC1 is a Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly. Synonyms: Polyclonal RCC1 antibody, Anti-RCC1 antibody, regulator of chromosome condensation 1 antibody, CHC1 antibody, RCC1-I antibody.

Pathways: Chromatin Binding, Protein targeting to Nucleus