WWOX Antikörper (C-Term)

Produktnummer ABIN926732

Produktdetails anti-WWOX Antikörper

Target: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WWOX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Purified

Immunogen: WWOX antibody was raised in rabbit using the C terminal of WWOX as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

WWOX Blocking Peptide, catalog no. 33R-10313, is also available for use as a blocking control in assays to test for specificity of this WWOX antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu WWOX

Target: WWOX (WW Domain Containing Oxidoreductase (WWOX))

Andere Bezeichnung: WWOX (WWOX Produkte)

Synonyme: CG7221 antikoerper, DmWWOX antikoerper, Dmel\\CG7221 antikoerper, anon-EST:Posey177 antikoerper, GB11795 antikoerper, WWOX antikoerper, D16S432E antikoerper, FOR antikoerper, FRA16D antikoerper, HHCMA56 antikoerper, PRO0128 antikoerper, SDR41C1 antikoerper, WOX1 antikoerper, zgc:55975 antikoerper, 5330426P09Rik antikoerper, 9030416C10Rik antikoerper, WW domain containing oxidoreductase antikoerper, WW domain-containing oxidoreductase antikoerper, Wwox antikoerper, LOC411815 antikoerper, WWOX antikoerper, CpipJ_CPIJ004939 antikoerper, MCYG_01584 antikoerper, VDBG_05631 antikoerper, VDBG_01326 antikoerper, VDBG_06753 antikoerper, Tsp_03967 antikoerper, LOC100284583 antikoerper, wwox antikoerper

Hintergrund: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. The encoded protein is more than 90% identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein. In addition, there is evidence that this gene behaves as a suppressor of tumor growth. Alternative splicing of this gene generates transcript variants that encode different isoforms. Synonyms: Polyclonal WWOX antibody, Anti-WWOX antibody, WW domain containing oxidoreductase antibody, D16S432E antibody, FOR antibody, FRA16D antibody, HHCMA56 antibody, PRO0128 antibody, SDR41C1 antibody, WOX1 antibody.