TNIP1 Antikörper (N-Term)

Produktnummer ABIN926782

Produktdetails anti-TNIP1 Antikörper

Target: TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Purified

Immunogen: TNIP1 antibody was raised in rabbit using the N terminal of TNIP1 as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

TNIP1 Blocking Peptide, catalog no. 33R-10405, is also available for use as a blocking control in assays to test for specificity of this TNIP1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu TNIP1

Target: TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))

Andere Bezeichnung: TNIP1 (TNIP1 Produkte)

Hintergrund: TNIP1 interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal. TNIP1 increases cell surface CD4(T4) antigen expression. TNIP1 interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. TNIP1 may regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production. Synonyms: Polyclonal TNIP1 antibody, Anti-TNIP1 antibody, TNFAIP3 interacting protein 1 antibody, ABIN-1 antibody, KIAA0113 antibody, NAF1 antibody, VAN antibody.

Pathways: Activation of Innate immune Response