Exportin 2 Antikörper (N-Term)

Produktnummer ABIN926854

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Exportin 2 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Huhn, Zebrafisch (Danio rerio) und Xenopus laevis.

Kurzübersicht für Exportin 2 Antikörper (N-Term) (ABIN926854)

Target: Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Huhn, Zebrafisch (Danio rerio), Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Exportin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Exportin 2 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Maus, Ratte (Rattus), Zebrafisch (Brachydanio rerio), Rind (Kuh), Frosch, Huhn

Aufreinigung: Purified

Immunogen: CSE1 L antibody was raised in rabbit using the N terminal of CSE1 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

CSE1L Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this CSE1L antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu Exportin 2

Target: Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

Andere Bezeichnung: CSE1L

Hintergrund: Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. CSE1L binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the protein may play a role both in apoptosis and in cell proliferation. Synonyms: Polyclonal CSE1L antibody, Anti-CSE1L antibody, CSE1 chromosome segregation 1-like, yeast antibody, CAS antibody, CSE1 antibody, MGC117283 antibody, MGC130036 antibody, MGC130037 antibody, XPO2 antibody.

Pathways: Protein targeting to Nucleus