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Insulin Receptor Antikörper (Middle Region)

Name: Insulin Receptor Antikörper (Middle Region)
Brand: antibodies-online
SKU: ABIN926933
Price: 1244.06 EUR
Availability: InStock

INSR Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Zebrafisch (Danio rerio), Xenopus laevis WB, IHC Wirt: Kaninchen Polyclonal unconjugated

INSR antibody (70R-10509) used at 2. (Insulin Receptor Antikörper (Middle Region))

INSR antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml. (Insulin Receptor Antikörper (Middle Region))

IHC

2 Abbildungen

Produktnummer ABIN926933

Datenblatt (PDF)

Target Alle Insulin Receptor (INSR) Antikörper anzeigen

Insulin Receptor (INSR)
Bindungsspezifität
16

14

14

10

8

8

7

5

5

5

5

4

4

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Middle Region
Reaktivität
172

88

77

16

11

9

8

7

6

5

4

3

2

1

1

1

1

1

1

1

1
Human, Maus, Ratte, Hund, Kaninchen, Zebrafisch (Danio rerio), Xenopus laevis
Wirt
158

29

2

1
Kaninchen
Passende Sekundärantikörper
Klonalität
146

44
Polyklonal
Konjugat
123

14

14

5

5

4

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser Insulin Receptor Antikörper ist unkonjugiert
Applikation
134

76

52

34

20

17

15

15

13

13

9

5

4

4

3

2

2

2

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

Kreuzreaktivität

Maus, Ratte (Rattus), Hund, Kaninchen, Zebrafisch (Brachydanio rerio), Frosch

Aufreinigung

Purified

Immunogen

INSR antibody was raised in rabbit using the middle region of INSR as the immunogen

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INSR Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Insulin Receptor (INSR) (AA 27-57), (N-Term) antibody
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Applikationshinweise

WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare

INSR Blocking Peptide, catalog no. 33R-8809, is also available for use as a blocking control in assays to test for specificity of this INSR antibody

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Lyophilized

Konzentration

Lot specific

Buffer

Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung

Avoid repeated freeze/thaw cycles.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
Target

Insulin Receptor (INSR)

Andere Bezeichnung

INSR (INSR Produkte)

Hintergrund

This receptor binds insulin and has a tyrosine-protein kinase activity. Isoform Short has a higher affinity for insulin. INSR mediates the metabolic functions of insulin. INSR binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). INSR can activate PI3K either directly by binding to the p85 regulatory subunit, or indirectly via IRS1. When present in a hybrid receptor with IGF1R, it binds IGF1. Synonyms: Polyclonal INSR antibody, Anti-INSR antibody, insulin receptor antibody, CD220 antibody, HHF5 antibody.

Pathways

NF-kappaB Signalweg, RTK Signalweg, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity