SNF8 Antikörper (N-Term)

Produktnummer ABIN927326

Produktdetails anti-SNF8 Antikörper

Target: SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Xenopus laevis, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNF8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Kreuzreaktivität: Maus, Ratte (Rattus), Frosch, Rind (Kuh), Hund, Huhn, Zebrafisch (Brachydanio rerio)

Aufreinigung: Purified

Immunogen: EAP30 antibody was raised in rabbit using the N terminal of EAP30 as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

EAP30 Blocking Peptide, catalog no. 33R-6102, is also available for use as a blocking control in assays to test for specificity of this EAP30 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu SNF8

Target: SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

Andere Bezeichnung: EAP30 (SNF8 Produkte)

Hintergrund: ELL encodes an RNA polymerase II transcription factor that undergoes frequent translocation in acute myeloid leukemia. In addition to its elongation activity, ELL contains a novel type of RNA polymerase II interaction domain that is capable of repressing polymerase activity in promoter-specific transcription. EAP30 is a subunit of the ELL complex. EAP30 can interact with ELL and derepress ELL's inhibitory activity in vitro.SNF8, VPS25, and VPS36 form ESCRT-II, a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8, VPS25, and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation factor. Synonyms: Polyclonal EAP30 antibody, Anti-EAP30 antibodyDot3 antibody, EAP30 antibody, VPS22 antibody.