DUSP12 Antikörper (N-Term)

Produktnummer ABIN927409

Produktdetails anti-DUSP12 Antikörper

Target: DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUSP12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus, Ratte (Rattus), Rind (Kuh)

Aufreinigung: Purified

Immunogen: DUSP12 antibody was raised in rabbit using the N terminal of DUSP12 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

DUSP12 Blocking Peptide, catalog no. 33R-9489, is also available for use as a blocking control in assays to test for specificity of this DUSP12 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu DUSP12

Target: DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))

Andere Bezeichnung: DUSP12 (DUSP12 Produkte)

Hintergrund: DUSP12 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. Synonyms: Polyclonal DUSP12 antibody, Anti-DUSP12 antibody, dual specificity phosphatase 12 antibody, DUSP1 antibody, YVH1 antibody.

Pathways: Regulation of Carbohydrate Metabolic Process