TIMELESS Antikörper (N-Term)

Produktnummer ABIN927477

Produktdetails anti-TIMELESS Antikörper

Target: TIMELESS (Timeless Homolog (TIMELESS))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIMELESS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Kreuzreaktivität: Maus, Ratte (Rattus), Rind (Kuh), Hund

Aufreinigung: Purified

Immunogen: TIMELESS antibody was raised in rabbit using the N terminal of TIMELESS as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

TIMELESS Blocking Peptide, catalog no. 33R-3969, is also available for use as a blocking control in assays to test for specificity of this TIMELESS antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu TIMELESS

Target: TIMELESS (Timeless Homolog (TIMELESS))

Andere Bezeichnung: TIMELESS (TIMELESS Produkte)

Synonyme: TIM antikoerper, TIM1 antikoerper, hTIM antikoerper, C77407 antikoerper, Debt69 antikoerper, tim antikoerper, CG3234 antikoerper, Dmel\\CG3234 antikoerper, Ritsu antikoerper, Tim antikoerper, dTIM antikoerper, dTim antikoerper, dtim antikoerper, mel_tim antikoerper, rit antikoerper, tim1 antikoerper, XTimeless1 antikoerper, timeless antikoerper, timelessb antikoerper, TIMELESS antikoerper, MXC20.14 antikoerper, MXC20_14 antikoerper, htim antikoerper, im:6903167 antikoerper, wu:fa95g04 antikoerper, wu:fd23d07 antikoerper, timeless circadian regulator antikoerper, timeless circadian clock 1 antikoerper, timeless antikoerper, timeless circadian clock antikoerper, timeless circadian clock S homeolog antikoerper, timeless family protein antikoerper, TIMELESS antikoerper, Timeless antikoerper, tim antikoerper, timeless.S antikoerper, Tim antikoerper, ATIM antikoerper, timeless antikoerper, LOC100328917 antikoerper

Hintergrund: The human Timeless protein interacts with both the circadian clock protein cryptochrome 2 and with the cell cycle checkpoint proteins Chk1 and the ATR-ATRIP complex and plays an important role in the DNA damage checkpoint response. Down-regulation of Timeless in human cells seriously compromises replication and intra-S checkpoints, indicating an intimate connection between the circadian cycle and the DNA damage checkpoints that is in part mediated by the Timeless protein. Synonyms: Polyclonal TIMELESS antibody, Anti-TIMELESS antibody, timeless homolog, Drosophila antibody.

Pathways: Protein targeting to Nucleus, Photoperiodism