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ACD Antikörper (C-Term)

ACD Reaktivität: Maus WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN927647
  • Target Alle ACD Antikörper anzeigen
    ACD (Adrenocortical Dysplasia Homolog (ACD))
    Bindungsspezifität
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 32
    • 12
    • 6
    • 3
    • 3
    • 3
    • 3
    • 1
    Maus
    Wirt
    • 26
    • 7
    • 1
    Kaninchen
    Klonalität
    • 29
    • 5
    Polyklonal
    Konjugat
    • 23
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ACD Antikörper ist unkonjugiert
    Applikation
    • 23
    • 10
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    Purified
    Immunogen
    Acd antibody was raised in rabbit using the c terminal of Acd as the immunogen
    Top Product
    Discover our top product ACD Primärantikörper
  • Applikationshinweise
    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.
    Kommentare

    Acd Blocking Peptide, catalog no. 33R-7345, is also available for use as a blocking control in assays to test for specificity of this Acd antibody

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Konzentration
    Lot specific
    Buffer
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • Target
    ACD (Adrenocortical Dysplasia Homolog (ACD))
    Andere Bezeichnung
    Acd (ACD Produkte)
    Synonyme
    PIP1 antikoerper, PTOP antikoerper, TINT1 antikoerper, TPP1 antikoerper, ACD antikoerper, ACD, shelterin complex subunit and telomerase recruitment factor antikoerper, adrenocortical dysplasia antikoerper, ACD antikoerper, Acd antikoerper
    Hintergrund
    Acd is a component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.Acd promotes binding of POT1 to single-stranded telomeric DNA.Acd modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomer elongation by increasing telomerase processivity.Acd plays a role in shelterin complex assembly. Acd may play an essential role in organogenesis of the developing embryo. Synonyms: Polyclonal Acd antibody, Anti-Acd antibody, adrenocortical dysplasia antibody.
    Pathways
    Telomere Maintenance
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