RENT2/UPF2 Antikörper (N-Term)

Produktnummer ABIN927943

Produktdetails anti-RENT2/UPF2 Antikörper

Target: RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RENT2/UPF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Purified

Immunogen: UPF2 antibody was raised in rabbit using the N terminal of UPF2 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu RENT2/UPF2

Target: RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))

Andere Bezeichnung: UPF2 (UPF2 Produkte)

Synonyme: HUPF2 antikoerper, RENT2 antikoerper, smg-3 antikoerper, UPF2, regulator of nonsense mediated mRNA decay antikoerper, UPF2 regulator of nonsense transcripts homolog (yeast) antikoerper, UPF2 antikoerper, Upf2 antikoerper, upf2 antikoerper

Hintergrund: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene, both variants encode the same protein. Synonyms: Polyclonal UPF2 antibody, Anti-UPF2 antibody, UPF2 regulator of nonsense transcripts homolog, yeast antibody, DKFZp434D222 antibody, HUPF2 antibody, KIAA1408 antibody, MGC138834 antibody, MGC138835 antibody, RENT2 antibody, smg-3 antibody.