SPOP-B Antikörper (C-Term)

Produktnummer ABIN928333

Produktdetails anti-SPOP-B Antikörper

Target: SPOP-B (Speckle-Type POZ Protein (SPOP-B))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Huhn, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPOP-B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus, Ratte (Rattus), Rind (Kuh), Frosch, Hund, Huhn, Zebrafisch (Brachydanio rerio)

Aufreinigung: Purified

Immunogen: SPOP antibody was raised in rabbit using the C terminal of SPOP as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

SPOP Blocking Peptide, catalog no. 33R-10118, is also available for use as a blocking control in assays to test for specificity of this SPOP antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu SPOP-B

Target: SPOP-B (Speckle-Type POZ Protein (SPOP-B))

Andere Bezeichnung: SPOP (SPOP-B Produkte)

Synonyme: BTBD32 antikoerper, TEF2 antikoerper, AI315626 antikoerper, Pcif1 antikoerper, zgc:64140 antikoerper, spop antikoerper, tef2 antikoerper, speckle type BTB/POZ protein antikoerper, speckle-type POZ protein antikoerper, speckle type POZ protein S homeolog antikoerper, SPOP antikoerper, Spop antikoerper, spop antikoerper, spop.S antikoerper

Hintergrund: SPOP may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Synonyms: Polyclonal SPOP antibody, Anti-SPOP antibody, speckle-type POZ protein antibody, TEF2 antibody.