FLASH Antikörper (N-Term)

Produktnummer ABIN928389

Produktdetails anti-FLASH Antikörper

Target: FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FLASH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus, Ratte (Rattus), Rind (Kuh), Hund

Aufreinigung: Purified

Immunogen: CASP8 AP2 antibody was raised in rabbit using the N terminal of CASP8 P2 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

CASP8AP2 Blocking Peptide, catalog no. 33R-8602, is also available for use as a blocking control in assays to test for specificity of this CASP8AP2 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu FLASH

Target: FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))

Andere Bezeichnung: CASP8AP2 (CASP8AP2 Produkte)

Synonyme: CASP8AP2 antikoerper, FLASH antikoerper, fc74h10 antikoerper, wu:fc74h10 antikoerper, zgc:113449 antikoerper, CED-4 antikoerper, RIP25 antikoerper, AA387232 antikoerper, D4Ertd659e antikoerper, mKIAA1315 antikoerper, caspase 8 associated protein 2 antikoerper, CASP8AP2 antikoerper, casp8ap2 antikoerper, Casp8ap2 antikoerper

Hintergrund: CASP8AP2 is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Synonyms: Polyclonal CASP8AP2 antibody, Anti-CASP8AP2 antibody, CASP8 associated protein 2 antibody, CED-4 antibody, FLASH antibody, FLJ11208 antibody, KIAA1315 antibody, RIP25 antibody.

Pathways: Chromatin Binding, Positive Regulation of Endopeptidase Activity