SIN3B Antikörper (Middle Region)

Produktnummer ABIN928395

Produktdetails anti-SIN3B Antikörper

Target: SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIN3B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus, Rind (Kuh)

Aufreinigung: Purified

Immunogen: SIN3 B antibody was raised in rabbit using the middle region of SIN3 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

SIN3B Blocking Peptide, catalog no. 33R-6663, is also available for use as a blocking control in assays to test for specificity of this SIN3B antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu SIN3B

Target: SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))

Andere Bezeichnung: SIN3B (SIN3B Produkte)

Synonyme: fj63d08 antikoerper, si:dkey-6n6.6 antikoerper, wu:fj63d08 antikoerper, 2810430C10Rik antikoerper, SIN3 transcription regulator family member B antikoerper, SIN3 transcription regulator family member B S homeolog antikoerper, transcriptional regulator, SIN3B (yeast) antikoerper, sin3b antikoerper, SIN3B antikoerper, sin3b.S antikoerper, Sin3b antikoerper

Hintergrund: SIN3B acts as a transcriptional repressor. It interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities.It also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. SIN3B also forms a complex with FOXK1 which represses transcription. Synonyms: Polyclonal SIN3B antibody, Anti-SIN3B antibody, SIN3 homolog B, transcription regulator, yeast antibody, KIAA0700 antibody.