PYHIN1 Antikörper (N-Term)

Produktnummer ABIN928476

Produktdetails anti-PYHIN1 Antikörper

Target: PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PYHIN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus, Ratte (Rattus), Rind (Kuh), Hund

Aufreinigung: Purified

Immunogen: PYHIN1 antibody was raised in rabbit using the N terminal of PYHIN1 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

PYHIN1 Blocking Peptide, catalog no. 33R-1404, is also available for use as a blocking control in assays to test for specificity of this PYHIN1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu PYHIN1

Target: PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))

Andere Bezeichnung: PYHIN1 (PYHIN1 Produkte)

Synonyme: IFIX antikoerper, RP11-520H16.1 antikoerper, 4930422C14 antikoerper, AI447904 antikoerper, Ifi209 antikoerper, Ifix antikoerper, pyrin and HIN domain family member 1 antikoerper, interferon activated gene 209 antikoerper, PYHIN1 antikoerper, Ifi209 antikoerper

Hintergrund: PYHIN1 belongs to the HIN-200 family. This protein is major mediator of the tumor suppressor activity of IFN in breast cancer cells. It promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization, and HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells. Synonyms: Polyclonal PYHIN1 antibody, Anti-PYHIN1 antibody, pyrin and HIN domain family, member 1 antibody, IFIX antibody, MGC23885 antibody, RP11-520H16.1 antibody.