MBNL2 Antikörper (Middle Region)

Produktnummer ABIN928546

Produktdetails anti-MBNL2 Antikörper

Target: MBNL2 (Muscleblind-Like 2 (MBNL2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MBNL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus, Ratte (Rattus), Hund, Huhn, Rind (Kuh), Zebrafisch (Brachydanio rerio)

Aufreinigung: Purified

Immunogen: MBNL2 antibody was raised in rabbit using the middle region of MBNL2 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

MBNL2 Blocking Peptide, catalog no. 33R-2607, is also available for use as a blocking control in assays to test for specificity of this MBNL2 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu MBNL2

Target: MBNL2 (Muscleblind-Like 2 (MBNL2))

Andere Bezeichnung: MBNL2 (MBNL2 Produkte)

Hintergrund: MBNL2 is a C3H-type zinc finger protein, which is similar to the Drosophila melanogaster muscleblind B protein.MBNL2 is a RNA-binding protein that binds to 5'ACACCC-3' core sequence. It binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. MBNL2 seems to regulate expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm. It may play a role in myotonic dystrophy pathophysiology (DM). Synonyms: Polyclonal MBNL2 antibody, Anti-MBNL2 antibody, muscleblind-like 2, Drosophila antibody, DKFZp781H1296 antibody, MBLL antibody, MBLL39 antibody, MGC120625 antibody, MGC120626 antibody, MGC120628 antibody, PRO2032 antibody.