PAXIP1 Antikörper (N-Term)

Produktnummer ABIN928548

Produktdetails anti-PAXIP1 Antikörper

Target: PAXIP1 (PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Hund, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAXIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus, Ratte (Rattus), Rind (Kuh), Hund, Frosch, Zebrafisch (Brachydanio rerio)

Aufreinigung: Purified

Immunogen: PAXIP1 antibody was raised in rabbit using the N terminal of PAXIP1 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

PAXIP1 Blocking Peptide, catalog no. 33R-5988, is also available for use as a blocking control in assays to test for specificity of this PAXIP1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu PAXIP1

Target: PAXIP1 (PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1))

Andere Bezeichnung: PAXIP1 (PAXIP1 Produkte)

Synonyme: CAGF29 antikoerper, PACIP1 antikoerper, PAXIP1L antikoerper, PTIP antikoerper, TNRC2 antikoerper, wu:fa04b06 antikoerper, zgc:92593 antikoerper, cagf28 antikoerper, cagf29 antikoerper, k14 antikoerper, pacip1 antikoerper, paxip1l antikoerper, ptip antikoerper, tnrc2 antikoerper, D5Ertd149e antikoerper, PAX interacting protein 1 antikoerper, PAX interacting (with transcription-activation domain) protein 1 antikoerper, PAX interacting protein 1 L homeolog antikoerper, PAXIP1 antikoerper, paxip1 antikoerper, paxip1.L antikoerper, Paxip1 antikoerper

Hintergrund: PAXIP1 functions as a key component of the DNA damage response, and phosphoserine or phosphothreonine-specific binding modules. PAXIP1 recognizes substrates phosphorylated by the kinases ataxia telangiectasia-mutated (ATM), ataxia telangiectasia and RAD3-related (ATR) in response to gamma irradiation. It may play a role in PAX2-dependent transcriptional regulation. PAXIP1 plays a role in early development, most probably in cell proliferation. Synonyms: Polyclonal PAXIP1 antibody, Anti-PAXIP1 antibody, PAX interacting, with transcription-activation domain protein 1 antibody, PTIP antibody, TNRC2 antibody, CAGF28 antibody, CAGF29 antibody, PACIP1 antibody, PAXIP1L antibody, FLJ41049 antibody.

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response