TXNIP Antikörper (Middle Region)
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- Target Alle TXNIP Antikörper anzeigen
- TXNIP (Thioredoxin Interacting Protein (TXNIP))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TXNIP Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Purified
- Immunogen
- TXNIP antibody was raised in rabbit using the middle region of TXNIP as the immunogen
- Top Product
- Discover our top product TXNIP Primärantikörper
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- Applikationshinweise
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - Kommentare
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TXNIP Blocking Peptide, catalog no. 33R-9486, is also available for use as a blocking control in assays to test for specificity of this TXNIP antibody
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Konzentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- TXNIP (Thioredoxin Interacting Protein (TXNIP))
- Andere Bezeichnung
- TXNIP (TXNIP Produkte)
- Synonyme
- EST01027 antikoerper, HHCPA78 antikoerper, THIF antikoerper, VDUP1 antikoerper, Gm348 antikoerper, Trf3 antikoerper, TBP2 antikoerper, TRF3 antikoerper, 1200008J08Rik antikoerper, AA682105 antikoerper, Hyplip1 antikoerper, Tbp-2 antikoerper, Vdup1 antikoerper, sb:cb368 antikoerper, txnip antikoerper, thioredoxin interacting protein antikoerper, TATA box binding protein like 2 antikoerper, TATA-box binding protein like 2 antikoerper, thioredoxin interacting protein L homeolog antikoerper, thioredoxin interacting protein a antikoerper, TXNIP antikoerper, Tbpl2 antikoerper, TBPL2 antikoerper, Txnip antikoerper, txnip.L antikoerper, txnip antikoerper, txnipa antikoerper
- Hintergrund
- TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. It interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells. Synonyms: Polyclonal TXNIP antibody, Anti-TXNIP antibody, thioredoxin interacting protein antibody, EST01027 antibody, HHCPA78 antibody, THIF antibody, VDUP1 antibody.
- Pathways
- Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
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