This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus, are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to bind the ATPase domain of the Hsp70-like Stch protein. Synonyms: Polyclonal UBQLN2 antibody, Anti-UBQLN2 antibody, ubiquilin 2 antibody, CHAP1 antibody, DSK2 antibody, FLJ10167 antibody, FLJ56541 antibody, HRIHFB2157 antibody, N4BP4 antibody, PLIC2 antibody.