MAGE-Like 2 Antikörper (C-Term)

Produktnummer ABIN929381

Produktdetails anti-MAGE-Like 2 Antikörper

Target: MAGE-Like 2 (MAGEL2)

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAGE-Like 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Purified

Immunogen: MAGEL2 antibody was raised in rabbit using the C terminal of MAGEL2 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

MAGEL2 Blocking Peptide, catalog no. 33R-6559, is also available for use as a blocking control in assays to test for specificity of this MAGEL2 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu MAGE-Like 2

Target: MAGE-Like 2 (MAGEL2)

Andere Bezeichnung: MAGEL2 (MAGEL2 Produkte)

Synonyme: NDNL1 antikoerper, nM15 antikoerper, MAGEL2 antikoerper, Mage-l2 antikoerper, ns7 antikoerper, MAGE family member L2 antikoerper, melanoma antigen, family L, 2 antikoerper, MAGEL2 antikoerper, Magel2 antikoerper

Hintergrund: Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS. Synonyms: Polyclonal MAGEL2 antibody, Anti-MAGEL2 antibody, MAGE-like 2 antibody, NDNL1 antibody, nM15 antibody.