ADRA1B Antikörper (C-Term)

Produktnummer ABIN929407

Produktdetails anti-ADRA1B Antikörper

Target: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADRA1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Purified

Immunogen: ADRA1 B antibody was raised in rabbit using the C terminal of ADRA1 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

ADRA1B Blocking Peptide, catalog no. 33R-10230, is also available for use as a blocking control in assays to test for specificity of this ADRA1B antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu ADRA1B

Target: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Andere Bezeichnung: ADRA1B (ADRA1B Produkte)

Synonyme: LOC100136712 antikoerper, [a]1b antikoerper, ADRA1 antikoerper, ALPHA1BAR antikoerper, RDC5 antikoerper, alpha-1B adrenoceptor antikoerper, adrenoceptor alpha 1B antikoerper, adrenergic receptor, alpha 1b antikoerper, LOC100136712 antikoerper, ADRA1B antikoerper, Adra1b antikoerper

Hintergrund: Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. Synonyms: Polyclonal ADRA1B antibody, Anti-ADRA1B antibody, adrenergic, alpha-1B-, receptor antibody, ADRA1 antibody, ALPHA1BAR antibody.

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process