Factor VII Antikörper (C-Term)

Produktnummer ABIN929426

Produktdetails anti-Factor VII Antikörper

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Factor VII Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Purified

Immunogen: F7 antibody was raised in rabbit using the C terminal of F7 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

F7 Blocking Peptide, catalog no. 33R-1026, is also available for use as a blocking control in assays to test for specificity of this F7 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu Factor VII

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Andere Bezeichnung: F7 (F7 Produkte)

Hintergrund: This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Alternative splicing of this gene results in 2 transcripts. Defects in this gene can cause coagulopathy. Synonyms: Polyclonal F7 antibody, Anti-F7 antibody, coagulation factor VII, serum prothrombin conversion accelerator antibody.

Pathways: Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling