CARD8 Antikörper

Produktnummer ABIN930979

Produktdetails anti-CARD8 Antikörper

Target: CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CARD8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Flow Cytometry (FACS), Dot Blot (DB)

Kreuzreaktivität: Human

Kreuzreaktivität (Details): Other species not studied.

Aufreinigung: Protein G affinity chromatography

Immunogen: CARD8 antibody was raised in mouse using recombinant Human Caspase Recruitment Domain Family, Member 8 (Card8)

Klon: 2108C2a

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 0.2-2 µg/mL, IP: 100-500 µg/sample, FC: 0.5-2 µg/sample, ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: CARD8 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Details zu CARD8

Target: CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))

Andere Bezeichnung: CARD8 (CARD8 Produkte)

Synonyme: CARD8 antikoerper, CARDINAL antikoerper, DACAR antikoerper, DAKAR antikoerper, NDPP antikoerper, NDPP1 antikoerper, TUCAN antikoerper, caspase recruitment domain family, member 8 antikoerper, caspase recruitment domain-containing protein 8 antikoerper, caspase recruitment domain family member 8 antikoerper, CARD8 antikoerper, LOC718594 antikoerper

Hintergrund: The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene. Synonyms: Monoclonal CARD8 antibody, Anti-CARD8 antibody, Caspase recruitment domain family antibody, DACAR antibody, NDPP1 antibody, TUCAN antibody, CARDINAL antibody, KIAA0955 antibody,MGC57162 antibody, DKFZp779L0366 antibody.

Pathways: Positive Regulation of Endopeptidase Activity