GAS41 Antikörper
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- Target Alle GAS41 Produkte
- GAS41 (YEATS Domain Containing 4)
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser GAS41 Antikörper ist unkonjugiert
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Applikation
- Dot Blot (DB)
- Kreuzreaktivität
- Human
- Kreuzreaktivität (Details)
- Other species not studied.
- Aufreinigung
- Protein G affinity chromatography
- Immunogen
- YEATS4 antibody was raised in mouse using recombinant Human Yeats Domain Containing 4 (Yeats4)
- Klon
- YEATB1A8
- Isotyp
- IgG1
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- Applikationshinweise
- Optimal conditions should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- Lot specific
- Buffer
- YEATS4 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handhabung
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
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- Target
- GAS41 (YEATS Domain Containing 4)
- Andere Bezeichnung
- YEATS4 (GAS41 Produkte)
- Hintergrund
- YEATS4 is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Synonyms: Monoclonal YEATS4 antibody, Anti-YEATS4 antibody, YEATS domain containing 4 antibody, YAF9 antibody, GAS41 antibody,NUBI-1 antibody, 4930573H17Rik antibody, B230215M10Rik antibody.
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