ARID4A Antikörper

Produktnummer ABIN931104

Produktdetails anti-ARID4A Antikörper

Target: ARID4A (AT Rich Interactive Domain 4A (RBP1-Like) (ARID4A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ARID4A Antikörper ist unkonjugiert

Applikation: Dot Blot (DB)

Kreuzreaktivität: Human

Kreuzreaktivität (Details): Other species not studied.

Aufreinigung: Protein G affinity chromatography

Immunogen: ARID4 A antibody was raised in mouse using recombinant Human At Rich Interactive Domain 4 (Rbp1-Like) (Arid4 )

Klon: 112C4a

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: ARID4 A antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Details zu ARID4A

Target: ARID4A (AT Rich Interactive Domain 4A (RBP1-Like) (ARID4A))

Andere Bezeichnung: ARID4A (ARID4A Produkte)

Hintergrund: The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described. Synonyms: Monoclonal ARID4A antibody, Anti-ARID4A antibody, AT rich interactive domain 4A antibody, RBP1 antibody, RBBP1 antibody, RBP-1 antibody.