SUPT4H Antikörper

Produktnummer ABIN932460

Produktdetails anti-SUPT4H Antikörper

Target: SUPT4H (SUPT4H1) (Suppressor of Ty 4 Homolog 1 (SUPT4H1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SUPT4H Antikörper ist unkonjugiert

Applikation: Dot Blot (DB)

Kreuzreaktivität: Human

Kreuzreaktivität (Details): Other species not studied.

Aufreinigung: Protein G affinity chromatography

Immunogen: SUPT4 H1 antibody was raised in mouse using recombinant Human Suppressor Of Ty 4 Homolog 1 (S. Cerevisiae) (Supt4 1)

Klon: 3079C1a

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: SUPT4 H1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Details zu SUPT4H

Target: SUPT4H (SUPT4H1) (Suppressor of Ty 4 Homolog 1 (SUPT4H1))

Andere Bezeichnung: SUPT4H1 (SUPT4H1 Produkte)

Synonyme: SPT4 antikoerper, SPT4H antikoerper, SUPT4H antikoerper, Supt4h2 antikoerper, AL022777 antikoerper, Supt4h antikoerper, Supt4h1 antikoerper, Supt4h1a antikoerper, 142904_at antikoerper, CG12372 antikoerper, DSIF antikoerper, Dmel\\CG12372 antikoerper, Dspt4 antikoerper, Spt4 antikoerper, dDSIF antikoerper, dspt4 antikoerper, l(2)k05316 antikoerper, DSIF small subunit antikoerper, spt4 antikoerper, zgc:92824 antikoerper, SPT4 homolog, DSIF elongation factor subunit antikoerper, suppressor of Ty 4A antikoerper, Transcription elongation factor SPT4 antikoerper, CG12372 gene product from transcript CG12372-RA antikoerper, SPT4 homolog, DSIF elongation factor subunit L homeolog antikoerper, transcription elongation factor antikoerper, transcription elongation factor complex subunit Spt4 antikoerper, SUPT4H1 antikoerper, Supt4h1 antikoerper, Supt4a antikoerper, spt-4 antikoerper, spt4 antikoerper, supt4h1.L antikoerper, CAALFM_C504630WA antikoerper, supt4h1 antikoerper

Hintergrund: SUPT4H1 is a component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II. Synonyms: Monoclonal SUPT4H1 antibody, Anti-SUPT4H1 antibody, Suppressor of Ty 4 homolog 1 antibody, SPT4H antibody, SUPT4H antibody.