BMP7 Antikörper

Produktnummer ABIN933774

Produktdetails anti-BMP7 Antikörper

Target: BMP7 (Bone Morphogenetic Protein 7 (BMP7))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BMP7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Aufreinigung: Protein A affinity chromatography

Immunogen: BMP7 antibody was raised in mouse using recombinant human BMP-7/OP-1 as the immunogen.

Klon: M912263

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: ELISA: 2-4 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized from PBS.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Details zu BMP7

Target: BMP7 (Bone Morphogenetic Protein 7 (BMP7))

Andere Bezeichnung: BMP7 (BMP7 Produkte)

Synonyme: bmp-7 antikoerper, bmp7 antikoerper, op-1 antikoerper, BMP7 antikoerper, zgc:153025 antikoerper, OP-1 antikoerper, OP1 antikoerper, BMP-7 antikoerper, fb83f09 antikoerper, wu:fb83f09 antikoerper, bone morphogenetic protein 7 antikoerper, bone morphogenetic protein 7, gene 1 L homeolog antikoerper, bone morphogenetic protein 7b antikoerper, bone morphogenetic protein 7, gene 2 L homeolog antikoerper, bone morphogenetic protein 7a antikoerper, BMP7 antikoerper, bmp7.1.L antikoerper, LOC100136282 antikoerper, bmp7b antikoerper, Bmp7 antikoerper, LOC100008826 antikoerper, bmp7.2.L antikoerper, bmp7a antikoerper

Hintergrund: TGF beta family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. BMP-7, also known as osteogenic protein-1 or OP-1, is a potent bone inducing agent, which in the presence of appropriate osteoconductive carrier (e.g. collagen sponge or synthetic hydroxyapatite) can be used in the treatment of bone defects. A bone-graft substitute, called OP-1TM implant, made of recombinant human BMP-7 associated with bovine bone-derived collagen, has recently been approved by the FDA as a device for treating critical-size bone fractures. Synonyms: Monoclonal BMP7 antibody, Anti-BMP7 antibody, BMP-7 antibody, Bone Morphogenetic antibody, 7 antibody,OP-1 antibody.

Molekulargewicht: 28.8 kDa (predicted detection band MW)

Pathways: Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance