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CD19 Antikörper

Name: CD19 Antikörper
Brand: antibodies-online
SKU: ABIN94013
Price: 293.28 EUR
Availability: InStock

CD19 Reaktivität: Human FACS, IP Wirt: Maus Monoclonal LT19 unconjugated

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD19 (LT19) purified antibody (concentration in sample 0,33 μg/mL, GAM APC). (CD19 Antikörper)

FACS

Surface staining of human peripheral blood cells with anti-human CD19 (LT19) APC. (CD19 Antikörper)

FACS

Separation of human CD19 positive lymphocytes (red-filled) from neutrofil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of peripheral whole blood stained using anti-human CD19 (LT19) purified antibody (concentration in sample 0,33 μg/mL, GAM APC). (CD19 Antikörper)

FACS

3 Abbildungen

(1 reference)

Produktnummer ABIN94013

Datenblatt (PDF)

Target Alle CD19 Antikörper anzeigen

CD19 (CD19 Molecule (CD19))
Reaktivität
292

165

41

29

19

10

7

5

4

3

2

2

2

2

2

2

2

2
Human
Wirt
183

130

57

4
Maus
Passende Sekundärantikörper
Klonalität
255

115

2
Monoklonal
Konjugat
125

25

22

22

19

10

9

8

8

7

5

5

5

4

4

4

4

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1
Dieser CD19 Antikörper ist unkonjugiert
Applikation
263

117

73

69

51

50

23

21

14

14

10

10

9

5

4

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Immunoprecipitation (IP)

Spezifität

The antibody LT19 reacts with an extracellular epitope of CD19 (B4), a 95 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed on B lymphocytes and follicular dendritic cells, it is lost on plasma cells.

Kreuzreaktivität (Details)

Human

Aufreinigung

Purified by protein-A affinity chromatography.

Reinheit

> 95 % (by SDS-PAGE)

Immunogen

Daudi human Burkitt lymphoma cell line

Klon

LT19

Isotyp

IgG1

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CD19 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Flow cytometry: Recommended dilution: 5 μg/mL.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1 mg/mL

Buffer

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Do not freeze.

Lagerung

4 °C

Informationen zur Lagerung

Store at 2-8°C. Do not freeze.
Kayserova, Vcelakova, Stechova, Dudkova, Hromadkova, Sumnik, Kolouskova, Spisek, Sediva: "Decreased dendritic cell numbers but increased TLR9-mediated interferon-alpha production in first degree relatives of type 1 diabetes patients." in: Clinical immunology (Orlando, Fla.), Vol. 153, Issue 1, pp. 49-55, (2014) (PubMed).
Target

CD19 (CD19 Molecule (CD19))

Andere Bezeichnung

CD19 (CD19 Produkte)

Hintergrund

CD19 Molecule,CD19 is a transmembrane glycoprotein of Ig superfamily expressed by B cells from the time of heavy chain rearrangement until plasma cell differentiation. It forms a tetrameric complex with CD21 (complement receptor type 2), CD81 (TAPA-1) and Leu13. Together with BCR (B cell antigen receptor), this complex signals to decrease B cell treshold for activation by the antigen. Besides being signal-amplifying coreceptor for BCR, CD19 can also signal independently of BCR coligation and it turns out to be a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.,B4, Leu-12, CVID3

Gen-ID

930

UniProt

P15391

Pathways

Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung