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CD19 Antikörper

Name: CD19 Antikörper
Brand: antibodies-online
SKU: ABIN94013
Price: 300.56 EUR
Availability: InStock

CD19 Reaktivität: Human FACS, IP Wirt: Maus Monoclonal LT19 unconjugated

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD19 (LT19) purified antibody (concentration in sample 0,33 μg/mL, GAM APC). (CD19 Antikörper)

FACS

Surface staining of human peripheral blood cells with anti-human CD19 (LT19) APC. (CD19 Antikörper)

FACS

Separation of human CD19 positive lymphocytes (red-filled) from neutrofil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of peripheral whole blood stained using anti-human CD19 (LT19) purified antibody (concentration in sample 0,33 μg/mL, GAM APC). (CD19 Antikörper)

FACS

3 Abbildungen

(1 reference)

Produktnummer ABIN94013

Datenblatt (PDF)

Target Alle CD19 Antikörper anzeigen

CD19 (CD19 Molecule (CD19))
Reaktivität
298

176

48

31

19

10

7

5

4

3

2

2

2

2

2

2

2

2
Human
Wirt
181

138

59

4
Maus
Passende Sekundärantikörper
Klonalität
249

129

2
Monoklonal
Konjugat
118

27

24

23

20

10

9

8

8

7

6

6

5

5

5

4

4

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1
Dieser CD19 Antikörper ist unkonjugiert
Applikation
261

122

74

66

50

48

22

21

14

14

11

11

10

5

4

4

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Immunoprecipitation (IP)

Spezifität

The antibody LT19 reacts with an extracellular epitope of CD19 (B4), a 95 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed on B lymphocytes and follicular dendritic cells, it is lost on plasma cells.

Kreuzreaktivität (Details)

Human

Aufreinigung

Purified by protein-A affinity chromatography.

Reinheit

> 95 % (by SDS-PAGE)

Immunogen

Daudi human Burkitt lymphoma cell line

Klon

LT19

Isotyp

IgG1

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anti-CD19 Molecule (CD19) (AA 143-172) antibody
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anti-CD19 Molecule (CD19) (AA 160-258) antibody
CD19 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-CD19 Molecule (CD19) antibody
CD19 Reaktivität: Human FACS, ICC Wirt: Maus Monoclonal 4G7 unconjugated

Applikationshinweise

Flow cytometry: Recommended dilution: 5 μg/mL.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1 mg/mL

Buffer

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Do not freeze.

Lagerung

4 °C

Informationen zur Lagerung

Store at 2-8°C. Do not freeze.
Kayserova, Vcelakova, Stechova, Dudkova, Hromadkova, Sumnik, Kolouskova, Spisek, Sediva: "Decreased dendritic cell numbers but increased TLR9-mediated interferon-alpha production in first degree relatives of type 1 diabetes patients." in: Clinical immunology (Orlando, Fla.), Vol. 153, Issue 1, pp. 49-55, (2014) (PubMed).
Target

CD19 (CD19 Molecule (CD19))

Andere Bezeichnung

CD19 (CD19 Produkte)

Synonyme

B4 antikoerper, CVID3 antikoerper, AW495831 antikoerper, CD19 antikoerper, CD19 molecule antikoerper, CD19 antigen antikoerper, CD19 antikoerper, Cd19 antikoerper

Hintergrund

CD19 Molecule,CD19 is a transmembrane glycoprotein of Ig superfamily expressed by B cells from the time of heavy chain rearrangement until plasma cell differentiation. It forms a tetrameric complex with CD21 (complement receptor type 2), CD81 (TAPA-1) and Leu13. Together with BCR (B cell antigen receptor), this complex signals to decrease B cell treshold for activation by the antigen. Besides being signal-amplifying coreceptor for BCR, CD19 can also signal independently of BCR coligation and it turns out to be a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.,B4, Leu-12, CVID3

Gen-ID

930

UniProt

P15391

Pathways

Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung