CD2 Antikörper
(2 Referenzen)-
- Target Alle CD2 Antikörper anzeigen
- CD2
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD2 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- Spezifität
- The antibody MEM-65 recognizes a unique extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T-lymphocytes and NK cells, also expressed by all thymocytes.
- Kreuzreaktivität (Details)
- Human
- Aufreinigung
- Purified by protein-A affinity chromatography.
- Reinheit
- > 95 % (by SDS-PAGE)
- Immunogen
- Human peripheral T cells.
- Klon
- MEM-65
- Isotyp
- IgG1
- Top Product
- Discover our top product CD2 Primärantikörper
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anti-CD2 (CD2) (AA 25-140) antibody
CD2 Reaktivität: Human FACS, WB, ELISA, IHC Wirt: Maus Monoclonal 3D1E3 unconjugated
anti-CD2 (CD2) (AA 25-140) antibodyCD2 Reaktivität: Human FACS, WB, ELISA, IHC Wirt: Maus Monoclonal 3D1B4 unconjugated
anti-CD2 (CD2) antibody (FITC)CD2 Reaktivität: Human FACS Wirt: Maus Monoclonal LT2 FITC
anti-CD2 (CD2) (N-Term) antibodyCD2 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD2 (CD2) antibody (PE)CD2 Reaktivität: Human FACS Wirt: Maus Monoclonal LT2 PE
anti-CD2 (CD2) (AA 1-351) antibodyCD2 Reaktivität: Human WB, IHC (p) Wirt: Maus Polyclonal unconjugated
anti-CD2 (CD2) antibodyCD2 Reaktivität: Human FACS, IF, WB, Func Wirt: Maus Monoclonal 1E7E8-G4 unconjugated
anti-CD2 (CD2) antibodyCD2 Reaktivität: Human FACS, IP Wirt: Maus Monoclonal LT2 unconjugated
anti-CD2 (CD2) antibodyCD2 Reaktivität: Human FACS, Func Wirt: Maus Monoclonal TS1-8 unconjugated
anti-CD2 (CD2) (AA 25-209) antibodyCD2 Reaktivität: Human IF, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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: "CD2 and TCR synergize for the activation of phospholipase Cgamma1/calcium pathway at the immunological synapse." in: International immunology, Vol. 19, Issue 3, pp. 239-48, (2007) (PubMed).
: "New monoclonal antibodies to human leucocyte surface molecule CD2." in: Folia biologica, Vol. 43, Issue 6, pp. 245-6, (1998) (PubMed).
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: "CD2 and TCR synergize for the activation of phospholipase Cgamma1/calcium pathway at the immunological synapse." in: International immunology, Vol. 19, Issue 3, pp. 239-48, (2007) (PubMed).
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- Target
- CD2
- Andere Bezeichnung
- CD2 (CD2 Produkte)
- Hintergrund
- CD2 Molecule,CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.,T11, LFA-2, SRBC
- Gen-ID
- 914
- UniProt
- P06729
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