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CD27 Antikörper

CD27 Reaktivität: Human FACS Wirt: Maus Monoclonal LT27 unconjugated
Produktnummer ABIN94051
  • Target Alle CD27 Antikörper anzeigen
    CD27 (CD27 Molecule (CD27))
    Reaktivität
    • 195
    • 71
    • 52
    • 5
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 110
    • 86
    • 22
    • 11
    • 3
    • 1
    • 1
    Maus
    Klonalität
    • 137
    • 95
    • 2
    Monoklonal
    Konjugat
    • 76
    • 24
    • 23
    • 15
    • 13
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD27 Antikörper ist unkonjugiert
    Applikation
    • 151
    • 80
    • 51
    • 38
    • 33
    • 20
    • 17
    • 14
    • 13
    • 13
    • 10
    • 9
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    The antibody LT27 reacts with an extracellular epitope of CD27 (T14), a 50-55 kDa type I transmembrane glycoprotein (member of the TNF-receptor superfamily) expressed on medullary thymocytes, peripheral T lymphocytes, some B lymphocytes and NK cells.
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    Human peripheral blood lymphocytes
    Klon
    LT27
    Isotyp
    IgG2a
    Top Product
    Discover our top product CD27 Primärantikörper
  • Applikationshinweise
    Flow cytometry: Recommended dilution: 2 μg/mL.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    CD27 (CD27 Molecule (CD27))
    Andere Bezeichnung
    CD27 (CD27 Produkte)
    Synonyme
    TNFRSF7 antikoerper, S152 antikoerper, Tnfrsf7 antikoerper, Tp55 antikoerper, S152. LPFS2 antikoerper, T14 antikoerper, CD27 molecule antikoerper, CD27 antigen antikoerper, CD27 antikoerper, Cd27 antikoerper
    Hintergrund
    CD27 Molecule,CD27 is a transmembrane 55 kDa protein of the nerve growth factor-receptor family, expressed as a disulfide-linked homodimer on mature thymocytes, peripheral blood T cells and a subpopulation of B cells. Activation of T cells via TCR-CD3 complex results in upregulation of CD27 expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. This sCD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T cells through the protease-activated receptors (PARs), degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70.,T14, TNFRSF7, LPFS2, S152, Tp55
    Gen-ID
    939
    UniProt
    P26842
    Pathways
    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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