CD27 Antikörper
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- Target Alle CD27 Antikörper anzeigen
- CD27 (CD27 Molecule (CD27))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD27 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- The antibody LT27 reacts with an extracellular epitope of CD27 (T14), a 50-55 kDa type I transmembrane glycoprotein (member of the TNF-receptor superfamily) expressed on medullary thymocytes, peripheral T lymphocytes, some B lymphocytes and NK cells.
- Kreuzreaktivität (Details)
- Human
- Aufreinigung
- Purified by protein-A affinity chromatography.
- Reinheit
- > 95 % (by SDS-PAGE)
- Immunogen
- Human peripheral blood lymphocytes
- Klon
- LT27
- Isotyp
- IgG2a
- Top Product
- Discover our top product CD27 Primärantikörper
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anti-CD27 Molecule (CD27) (AA 1-260) antibody
CD27 Reaktivität: Human WB, ELISA, RNAi Wirt: Maus Monoclonal 1E2-A3 unconjugated
anti-CD27 Molecule (CD27) antibodyCD27 Reaktivität: Human FACS, ELISA, IHC, IF, StM, Coat Wirt: Maus Monoclonal LPFS2-1611 unconjugated
anti-CD27 Molecule (CD27) antibodyCD27 Reaktivität: Human, Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-CD27 Molecule (CD27) (AA 20-191) antibodyCD27 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-CD27 Molecule (CD27) (AA 20-144) antibodyCD27 Reaktivität: Human FACS, ELISA Wirt: Maus Monoclonal 3B6D3 unconjugated
anti-CD27 Molecule (CD27) (AA 196-225) antibodyCD27 Reaktivität: Human FACS, WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-CD27 Molecule (CD27) (AA 229-312) antibodyCD27 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-CD27 Molecule (CD27) (AA 196-225), (C-Term) antibodyCD27 Reaktivität: Human FACS, WB Wirt: Kaninchen Polyclonal RB33726 unconjugated
anti-CD27 Molecule (CD27) antibodyCD27 Reaktivität: Human FACS, IHC, StM Wirt: Maus Monoclonal rLPFS2-1611 unconjugated Recombinant Antibody
anti-CD27 Molecule (CD27) antibodyCD27 Reaktivität: Human WB, IF Wirt: Kaninchen Monoclonal unconjugated
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- Applikationshinweise
- Flow cytometry: Recommended dilution: 2 μg/mL.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- Target
- CD27 (CD27 Molecule (CD27))
- Andere Bezeichnung
- CD27 (CD27 Produkte)
- Hintergrund
- CD27 Molecule,CD27 is a transmembrane 55 kDa protein of the nerve growth factor-receptor family, expressed as a disulfide-linked homodimer on mature thymocytes, peripheral blood T cells and a subpopulation of B cells. Activation of T cells via TCR-CD3 complex results in upregulation of CD27 expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. This sCD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T cells through the protease-activated receptors (PARs), degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70.,T14, TNFRSF7, LPFS2, S152, Tp55
- Gen-ID
- 939
- UniProt
- P26842
- Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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