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Integrin Alpha2b Antikörper (Biotin)

Name: Integrin Alpha2b Antikörper (Biotin)
Brand: antibodies-online
SKU: ABIN94107
Price: 366.6 EUR
Availability: InStock

CD41 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-06 Biotin

Flow cytometry analysis (surface staining) of human platelets with anti-human CD41 (MEM-06) biotin, streptavidin-APC. (Integrin Alpha2b Antikörper (Biotin))

FACS

Surface staining of human platelets with anti-human CD41 (MEM-06) PE. (Integrin Alpha2b Antikörper (Biotin))

FACS

2 Abbildungen

(1 reference)

Produktnummer ABIN94107

Datenblatt (PDF)

Target Alle Integrin Alpha2b (CD41) Antikörper anzeigen

Integrin Alpha2b (CD41)
Reaktivität
122

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Human
Wirt
78

46

26
Maus
Passende Sekundärantikörper
Klonalität
100

44

1
Monoklonal
Konjugat
58

16

12

11

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4

4

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3

2

2

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Dieser Integrin Alpha2b Antikörper ist konjugiert mit Biotin
Applikation
102

44

27

27

20

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Flow Cytometry (FACS)

Spezifität

The antibody MEM-06 reacts with an extracellular epitope of CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain, 120 kDa) and GPIIb beta (light chain, 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.

Kreuzreaktivität (Details)

Human

Aufreinigung

Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.

Immunogen

Leukocytes of patient suffering from LGL-type leukaemia.

Klon

MEM-06

Isotyp

IgG1

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anti-Integrin Alpha2b (CD41) antibody (PE)
CD41 Reaktivität: Maus FACS Wirt: Ratte Monoclonal MWReg30 PE

Applikationshinweise

Flow cytometry: Recommended dilution: 2 μg/mL.

Kommentare

The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1 mg/mL

Buffer

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Do not freeze.
Avoid prolonged exposure to light.

Lagerung

4 °C

Informationen zur Lagerung

Store at 2-8°C. Do not freeze.
Karimi, Dalirfardouei, Dias, Lötvall, Lässer: "Tetraspanins distinguish separate extracellular vesicle subpopulations in human serum and plasma - Contributions of platelet extracellular vesicles in plasma samples." in: Journal of extracellular vesicles, Vol. 11, Issue 5, pp. e12213, (2022) (PubMed).
Target

Integrin Alpha2b (CD41)

Andere Bezeichnung

CD41 (CD41 Produkte)

Synonyme

AI172977 antikoerper, CD41 antikoerper, CD41B antikoerper, GpIIb antikoerper, alphaIIb antikoerper, BDPLT16 antikoerper, BDPLT2 antikoerper, GP2B antikoerper, GPIIb antikoerper, GT antikoerper, GTA antikoerper, HPA3 antikoerper, integrin alpha 2b antikoerper, integrin subunit alpha 2b antikoerper, Itga2b antikoerper, ITGA2B antikoerper

Hintergrund

Integrin subunit alpha 2b,CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.,Platelet GPIIb, Integrin alpha-IIb, GPalpha IIb, GTA

Gen-ID

3674

UniProt

P08514

Pathways

Integrin Complex