Integrin Alpha2b Antikörper
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- Target Alle Integrin Alpha2b (CD41) Antikörper anzeigen
- Integrin Alpha2b (CD41)
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Reaktivität
- Human, Non-Human Primate
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Integrin Alpha2b Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- The antibody HIP2 reacts with an extracellular epitope on beta (b) subunit of CD41 glycoprotein (light chain, 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.
- Kreuzreaktivität (Details)
- Human, Non-Human Primates
- Aufreinigung
- Purified by protein-A affinity chromatography.
- Reinheit
- > 95 % (by SDS-PAGE)
- Klon
- HIP2
- Isotyp
- IgG3
- Top Product
- Discover our top product CD41 Primärantikörper
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- Applikationshinweise
- Flow cytometry: Recommended dilution: 1-4 μg/mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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[Production and application of anti-human platelet GP IIb/IIIa monoclonal antibodies]." in: Zhonghua yi xue za zhi, Vol. 69, Issue 8, pp. 427-30, 30, (1990) (PubMed).
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[Production and application of anti-human platelet GP IIb/IIIa monoclonal antibodies]." in: Zhonghua yi xue za zhi, Vol. 69, Issue 8, pp. 427-30, 30, (1990) (PubMed).
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- Target
- Integrin Alpha2b (CD41)
- Andere Bezeichnung
- CD41b (CD41 Produkte)
- Hintergrund
- Integrin subunit alpha 2b,CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.,GT, GTA, GP2B, HPA3, GPIIb
- Gen-ID
- 3674
- UniProt
- P08514
- Pathways
- Integrin Complex
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