CD56 Antikörper (Biotin)
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- Target Alle CD56 (NCAM1) Antikörper anzeigen
- CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))
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Reaktivität
- Human, Non-Human Primate
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD56 Antikörper ist konjugiert mit Biotin
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Applikation
- Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
- Spezifität
- The antibody MEM-188 reacts with an extracellular epitope on a 180 kDa isoform of CD56 (NCAM) expressed in leukocytes. It has been suggested that the antibody MEM-188 could react with rhesus monkey lymphocytes. Reactivity with other NCAM isoforms has not been tested.
- Kreuzreaktivität (Details)
- Human, Non-Human Primates
- Aufreinigung
- Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
- Immunogen
- KG-1 human acute myelogenous leukemia cell line
- Klon
- MEM-188
- Isotyp
- IgG2a
- Top Product
- Discover our top product NCAM1 Primärantikörper
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- Applikationshinweise
- Flow cytometry: Recommended dilution: 2-5 μg/mL.
- Kommentare
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The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
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Do not freeze.
Avoid prolonged exposure to light. - Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses." in: BMC immunology, Vol. 12, pp. 2, (2011) (PubMed).
: "Isolation of Mycobacterium avium subspecies paratuberculosis reactive CD4 T cells from intestinal biopsies of Crohn's disease patients." in: PLoS ONE, Vol. 4, Issue 5, pp. e5641, (2009) (PubMed).
: "Single-molecule microscopy reveals heterogeneous dynamics of lipid raft components upon TCR engagement." in: International immunology, Vol. 19, Issue 5, pp. 675-84, (2007) (PubMed).
: "The maintenance of human CD4+ CD25+ regulatory T cell function: IL-2, IL-4, IL-7 and IL-15 preserve optimal suppressive potency in vitro." in: International immunology, Vol. 19, Issue 6, pp. 785-99, (2007) (PubMed).
: "LIME: a new membrane Raft-associated adaptor protein involved in CD4 and CD8 coreceptor signaling." in: The Journal of experimental medicine, Vol. 198, Issue 10, pp. 1453-62, (2003) (PubMed).
: "Non-T cell activation linker (NTAL): a transmembrane adaptor protein involved in immunoreceptor signaling." in: The Journal of experimental medicine, Vol. 196, Issue 12, pp. 1617-26, (2002) (PubMed).
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Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses." in: BMC immunology, Vol. 12, pp. 2, (2011) (PubMed).
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- Target
- CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))
- Andere Bezeichnung
- CD56 (NCAM1 Produkte)
- Synonyme
- CD56 antikoerper, MSK39 antikoerper, NCAM antikoerper, fj56g09 antikoerper, ncam antikoerper, ncam1 antikoerper, wu:fj56g09 antikoerper, NCAM1 antikoerper, n-cam antikoerper, E-NCAM antikoerper, NCAM-1 antikoerper, Ncam antikoerper, Cd56 antikoerper, N-CAM antikoerper, N-CAM-1 antikoerper, NCAM-C antikoerper, NCAMC antikoerper, N-CAM-1-B antikoerper, NCAM-1-B antikoerper, ncam1-a antikoerper, ncam1-b antikoerper, neural cell adhesion molecule 1 antikoerper, neural cell adhesion molecule 1a antikoerper, neural cell adhesion molecule 1 S homeolog antikoerper, neural cell adhesion molecule 1 L homeolog antikoerper, NCAM1 antikoerper, ncam1a antikoerper, ncam1 antikoerper, LOC100085373 antikoerper, ncam1.S antikoerper, Ncam1 antikoerper, ncam1.L antikoerper
- Hintergrund
- Neural cell adhesion molecule 1,CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120 kDa, 140 kDa or 180 kDa isoform, and it is also found on T cells and NK cells. Polysialic modification results in reduction of CD56-mediated cell adhesion and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumours and ovarian granulosa cell tumours.,NCAM1, MSK39
- Gen-ID
- 4684
- UniProt
- P13591
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