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L-Selectin Antikörper

Name: L-Selectin Antikörper
Brand: antibodies-online
SKU: ABIN94209
Price: 273.24 EUR
Availability: InStock

SELL Reaktivität: Human, Rind (Kuh) FACS, IP, ICC Wirt: Maus Monoclonal IVA94 unconjugated

Flow cytometry surface staining pattern of bovine peripheral whole blood stained using anti-bovine CD62L (IVA94) purified antibody (concentration in sample 1 μg/mL) GAM APC. (L-Selectin Antikörper)

FACS

Immunocytochemistry staining of acetone/methanol fixed bovine peripheral blood (lymphocyte-enriched suspension) using anti-bovine CD62L (IVA94), secondary antibody conjugated to FITC (green), DNA stained with DAPI (blue). (L-Selectin Antikörper)

ICC

Separation of bovine CD62L positive lymphocytes (red-filled) from CD62L negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of bovine peripheral whole blood stained using anti-bovine CD62L (IVA94) purified antibody (concentration in sample 1 μg/mL) GAM APC. (L-Selectin Antikörper)

FACS

3 Abbildungen

(3 Referenzen)

Produktnummer ABIN94209

Datenblatt (PDF)

Target Alle L-Selectin (SELL) Antikörper anzeigen

L-Selectin (SELL) (Selectin L (SELL))
Reaktivität
104

72

44

34

8

6

4

3

2

2

1
Human, Rind (Kuh)
Wirt
97

73

50

1
Maus
Passende Sekundärantikörper
Klonalität
167

49

3
Monoklonal
Konjugat
76

30

24

18

13

8

6

6

5

5

4

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1
Dieser L-Selectin Antikörper ist unkonjugiert
Applikation
164

66

58

52

33

23

18

12

11

10

8

7

4

4

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Spezifität

The antibody IVA94 reacts with an extracellular epitope of CD62L antigen (bovine). CD62L (L-selectin) is a 74-95 kDa single chain type I glycoprotein expressed on most peripheral blood B lymphocytes, T lymphocytes, monocytes and granulocytes, it is also present on a subset of NK cells and certain hematopoietic malignant cells.

Kreuzreaktivität (Details)

Bovine

Aufreinigung

Purified by protein-A affinity chromatography.

Reinheit

> 95 % (by SDS-PAGE)

Immunogen

Bovine leukocytes.

Klon

IVA94

Isotyp

IgG1

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Applikationshinweise

Flow cytometry: Recommended dilution: 1-4 μg/mL.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1 mg/mL

Buffer

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Do not freeze.

Lagerung

4 °C

Informationen zur Lagerung

Store at 2-8°C. Do not freeze.
Howard: "Ruminant cluster CD62L." in: Veterinary immunology and immunopathology, Vol. 52, Issue 4, pp. 255-6, (1997) (PubMed).

Naessens, Nthale, Muiya: "Biochemical analysis of preliminary clusters in the non-lineage panel." in: Veterinary immunology and immunopathology, Vol. 52, Issue 4, pp. 347-56, (1997) (PubMed).

Naessens, Howard, Hopkins: "Nomenclature and characterization of leukocyte differentiation antigens in ruminants." in: Immunology today, Vol. 18, Issue 8, pp. 365-8, (1997) (PubMed).
Target

L-Selectin (SELL) (Selectin L (SELL))

Andere Bezeichnung

CD62L (SELL Produkte)

Synonyme

CD62L antikoerper, LAM1 antikoerper, LECAM1 antikoerper, LEU8 antikoerper, LNHR antikoerper, LSEL antikoerper, LYAM1 antikoerper, PLNHR antikoerper, TQ1 antikoerper, A.11 antikoerper, L-selectin antikoerper, LECAM-1 antikoerper, SELE antikoerper, AI528707 antikoerper, Lnhr antikoerper, Ly-22 antikoerper, Ly-m22 antikoerper, Lyam-1 antikoerper, Lyam1 antikoerper, selectin L antikoerper, selectin, lymphocyte antikoerper, SELL antikoerper, Sell antikoerper

Hintergrund

Selectin L,CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1).,L-selectin, LSEL, SELL, LAM1, LECAM1, LEU8, LNHR, LYAM1, PLNHR

Gen-ID

281485

UniProt

P98131