L-Selectin Antikörper
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- Target Alle L-Selectin (SELL) Antikörper anzeigen
- L-Selectin (SELL) (Selectin L (SELL))
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Reaktivität
- Human, Rind (Kuh)
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser L-Selectin Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)
- Spezifität
- The antibody IVA94 reacts with an extracellular epitope of CD62L antigen (bovine). CD62L (L-selectin) is a 74-95 kDa single chain type I glycoprotein expressed on most peripheral blood B lymphocytes, T lymphocytes, monocytes and granulocytes, it is also present on a subset of NK cells and certain hematopoietic malignant cells.
- Kreuzreaktivität (Details)
- Bovine
- Aufreinigung
- Purified by protein-A affinity chromatography.
- Reinheit
- > 95 % (by SDS-PAGE)
- Immunogen
- Bovine leukocytes.
- Klon
- IVA94
- Isotyp
- IgG1
- Top Product
- Discover our top product SELL Primärantikörper
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- Applikationshinweise
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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Ruminant cluster CD62L." in: Veterinary immunology and immunopathology, Vol. 52, Issue 4, pp. 255-6, (1997) (PubMed).
: "Biochemical analysis of preliminary clusters in the non-lineage panel." in: Veterinary immunology and immunopathology, Vol. 52, Issue 4, pp. 347-56, (1997) (PubMed).
: "Nomenclature and characterization of leukocyte differentiation antigens in ruminants." in: Immunology today, Vol. 18, Issue 8, pp. 365-8, (1997) (PubMed).
: "
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Ruminant cluster CD62L." in: Veterinary immunology and immunopathology, Vol. 52, Issue 4, pp. 255-6, (1997) (PubMed).
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- Target
- L-Selectin (SELL) (Selectin L (SELL))
- Andere Bezeichnung
- CD62L (SELL Produkte)
- Hintergrund
- Selectin L,CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1).,L-selectin, LSEL, SELL, LAM1, LECAM1, LEU8, LNHR, LYAM1, PLNHR
- Gen-ID
- 281485
- UniProt
- P98131
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