CD8 Antikörper
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- Target Alle CD8 Antikörper anzeigen
- CD8
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD8 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- Spezifität
- The antibody MEM-87 recognizes an extracellular epitope of CD8, a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 is a disulfide-linked dimer and exists as a CD8 alpha/alpha homodimer or CD8 alpha/beta heterodimer (each monomer approx. 32-34 kDa).
- Kreuzreaktivität (Details)
- Human
- Aufreinigung
- Purified by protein-A affinity chromatography.
- Reinheit
- > 95 % (by SDS-PAGE)
- Immunogen
- Leukocytes of a patient suffering from LGL Type Leukemia.
- Klon
- MEM-87
- Isotyp
- IgG1
- Top Product
- Discover our top product CD8 Primärantikörper
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anti-CD8 (CD8) (AA 51-150) antibody
CD8 Reaktivität: Human, Maus, Ratte FACS, IHC (fro), WB, ELISA, IHC (p), IF (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
anti-CD8 (CD8) antibody (PE)CD8 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-31 PE
anti-CD8 (CD8) (AA 22-187) antibodyCD8 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD8 (CD8) antibodyCD8 Reaktivität: Human FACS, IP, CyTOF Wirt: Maus Monoclonal MEM-31 unconjugated
anti-CD8 (CD8) antibody (Biotin)CD8 Reaktivität: Human FACS, IP Wirt: Maus Monoclonal MEM-31 Biotin
anti-CD8 (CD8) antibody (FITC)CD8 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-31 FITC
anti-CD8 (CD8) antibodyCD8 Reaktivität: Human IHC, IP, WB, ELISA Wirt: Kaninchen Monoclonal 3C3 unconjugated Recombinant Antibody
anti-CD8 (CD8) antibody (PerCP)CD8 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-31 PerCP
anti-CD8 (CD8) antibody (APC)CD8 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-31 APC
anti-CD8 (CD8) antibody (PE)CD8 Reaktivität: Cat FACS Wirt: Maus Monoclonal fCD8 PE
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- Applikationshinweise
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Flow cytometry: Recommended dilution: 2 μg/mL.
Immunoprecipitation: Excellent for immunoisolation of CD8 positive T cells. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- Target
- CD8
- Andere Bezeichnung
- CD8 (CD8 Produkte)
- Synonyme
- CD8 antikoerper, Leu2 antikoerper, MAL antikoerper, p32 antikoerper, CD8a molecule antikoerper, CD8A antikoerper
- Hintergrund
- The CD8 T cell coreceptor (monomer approx. 32-34 kDa) is expressed as alpha/beta heterodimer on majority of MHC I-restricted conventional T cells and thymocytes and as alpha/alpha homodimer on subsets of memory T cells, intraepithelial lymphocytes, NK cells and dendritic cells. Regulation of CD8 beta level on T cell surface seems to be an important mechanism to control their effector function. Assembly of CD8 alpha-beta but not alpha-alpha dimers is connected with formation or localization to the lipid rafts. Recruiting triggered TCR complexes to these membrane microdomains as well as affinity of TCR to MHC I is modulated by CD8, thereby affecting the functional diversity of the TCR signaling.,p32, LEU2
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