Keratin 5/8 Antikörper
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- Target Alle Keratin 5/8 (KRT5/8) Produkte
- Keratin 5/8 (KRT5/8)
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Reaktivität
- Human, Maus, Schwein, Ratte, Hund, Hamster, Rind (Kuh), Schaf
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Keratin 5/8 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunoprecipitation (IP)
- Spezifität
- The antibody C-50 reacts with cytokeratin peptides 5 and 8 (58 and 53 kDa). Cytokeratins are members of intermediate filaments subfamily of intracellular proteins represented in epithelial tissues.
- Keine Kreuzreaktivität
- Huhn, Xenopus laevis
- Kreuzreaktivität (Details)
- Human, Sheep, Canine (Dog), Hamster, Mouse, Rat, Bovine, Porcine
- Aufreinigung
- Purified by protein-A affinity chromatography.
- Reinheit
- > 95 % (by SDS-PAGE)
- Immunogen
- Cytoskeleton preparation from HeLa cells.
- Klon
- C-50
- Isotyp
- IgG1
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- Applikationshinweise
- Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/mL, positive control: human prostate.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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A series of 14 new monoclonal antibodies to keratins: characterization and value in diagnostic histopathology." in: The Journal of pathology, Vol. 164, Issue 3, pp. 215-24, (1991) (PubMed).
: "
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A series of 14 new monoclonal antibodies to keratins: characterization and value in diagnostic histopathology." in: The Journal of pathology, Vol. 164, Issue 3, pp. 215-24, (1991) (PubMed).
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- Target
- Keratin 5/8 (KRT5/8)
- Andere Bezeichnung
- Cytokeratin 5+8 (KRT5/8 Produkte)
- Hintergrund
- Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. They are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.,K5, K8, CK5, CK8, CYK5, CYK8, KRT5, KRT8
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