HLA-DQ1/DQ3 Antikörper

Produktnummer ABIN94338

Produktdetails anti-HLA-DQ1/DQ3 Antikörper

Target: HLA-DQ1/DQ3 (MHC Class II HLA-DQ1/DQ3 (HLA-DQ1/DQ3))

Reaktivität: Human, Schwein

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HLA-DQ1/DQ3 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP)

Spezifität: The antibody HL-37 reacts with extracellular polymorphic determinant on human HLA-DQ1 and HLA-DQ3 Molecules (recognized epitope was found on isolated beta chain of DQ1), but does not react with HLA-DQ2. DQ is the isotype of human MHC Class II molecules expressed on antigen-presenting cells (APC, dendritic cells, B lymphocytes, monocytes, macrophages).

Kreuzreaktivität (Details): Human, Porcine

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: Burkitt's lymphoma cell line Raji.

Klon: HL-37

Isotyp: IgG3

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-4 μg/mL.
Western blotting: non-reducing conditions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Referenzen für anti-HLA-DQ1/DQ3 Antikörper (ABIN94338)

Horejsí, N?mec, Angelisová, Kristofová, Gorga, Hilgert: "Characterization of seven new monoclonal antibodies against human DR, DR + DP and DQ1 + DQ3 antigens." in: Tissue antigens, Vol. 28, Issue 5, pp. 288-97, (1987) (PubMed).

Details zu HLA-DQ1/DQ3

Target: HLA-DQ1/DQ3 (MHC Class II HLA-DQ1/DQ3 (HLA-DQ1/DQ3))

Andere Bezeichnung: HLA-DQ1+DQ3 (HLA-DQ1/DQ3 Produkte)

Hintergrund: The antibody HL-37 reacts with polymorphic determinant on human HLA-DQ1 and HLA-DQ3 Molecules (recognized epitope was found on isolated beta chain of DQ1), but does not react with HLA-DQ2. DQ is the isotype of human MHC Class II molecules expressed on antigen-presenting cells (APC, dendritic cells, B lymphocytes, monocytes, macrophages).